Systemic Scleroderma

　　Years ago, only the worst cases of scleroderma were diagnosed, thus leading to the widespread belief that systemic scleroderma was always progressive and fatal.

　　以前，只有最严重的硬皮病患者得到诊断，这就导致了广泛的认识，系统性硬皮病是不断进展的并且是致命的。

1. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
   Preliminary criteria for the classification of systemic sclerosis (scleroderma)
2. Effects of prostaglandin E1α cyclodestrin treatment on endothelial dysfunction in patients with systemic sclerosis
   Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls.
3. Pulmonary hypertension in the crest syndrome variant of systemic sclerosis
   Systemic sclerosis: a prototypic multisystem fibrotic disorder
4. Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach
   Membranoproliferative glomerulonephritis in systemic sclerosis of childhood
5. Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist.
   Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis